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Master’s Degree in BIOTECHNOLOGY
Speciality : Formulation et vectorization of biomolecules

 

Competences

 
Analytical technics  : Circular dichroism, light scattering, NMR, Mass
                                      spectrometry, IR,  HPLC,
GC

Biology : Formulation and vectorization (proteins, nucleic acids, small organic
                molecules )

             Immunologie (ELISA, Western Blot)

                enzymologie (enzyme immobolization, Bioconversion,enzymatic tests)

Chemistry: Peptidic Synthesis, organic synthesis, asymetric synthesis,
                  nucleosidic synthesis,  organometallic chemistry...

Computer :        softwares (Word, Excel, Powerpoint, chemdraw...), 
                           
Internet (web sites creation with HTML PHP, javascript...), 
                          bioinformatic (sequences algnment, genes prediction,                                             3D structure proteins prediction ).

jLanguages : french (mother tong), working knowledge of English

Education

Since june 2006 : PhD study on the biomolecules vectorization

May 2005 : Diplôme de Recherche Technologique. Equivalent to a six-year
                 university degree in Biotechnology.    

Juin 2003 :Ingénieur en biotechnologie. Equivalent to a five-year university degree
                in Biotechnology.

Juin 2001 :Master’s degree in organic chemistry. Speciality synthesis, purification
                and analysis of biomolecules

professional experiences

Since 2005 : Research mission in a drug delivery company

- Therapeutical proteins formulation for nasal delivery
- Vaccinating proteins formulation for nasal delivery
- Biomolecules formulation for topical administration
- Peptide formulation for intravenous administration
- Supervisation of preclinic studies in the rabbit
- Chemical synthesis of enhancer for nasal delivery
- stability analysis of formulated proteins by circular dichroïsm
- Formulated proteins hydrodynamic radius determined by light scattering

2002 : Research mission of 6 months in a pharmaceutical company

- Chemical synthesis of IL-8 inhibitor receptors
- multistep synthesis of phenylsulfonamid
- Use of GC for the calculation of endo/exo product proportions generated by a
  chemical reaction
- stereoisomer separation by HPLC
- synthesis product control by NMR

2001 : Research mission of 4 months in the LAPP group (UMR 5810)

- chemical synthesis of a tetrapeptide
- Chemical cyclisation of the tetrapeptide in order to increase its lipophylicity
- purity synthesized peptide determined by HPLC
- Control of the synthesized peptide by NMR

Publications

C. Bijani, S. Varray, R. Lazaro, J. Martinez, F. Lamaty, N. Kieffer. Cyclic RGD peptide by ring-closing metathesis. Tetrahedron Letters 43 (2002) 3765 – 3767.

A. Aramini,* M. C. Cesta, S. Coniglio, C. Bijani, S. Colagioia, V. D'Elia, and M. Allegretti*. Synthesis of E-Aryl Ethenesulfonamides: A Simple One-Pot, Two-Step Procedure from 1-Hydroxy-1-arylalkanes. J. Org. Chem., 68 (2003), 7911 -7914

Interests

IInformatic, internet, web sites creation
Astronomy and astrophotography

 

 

 

 

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